Gastro-Oesophageal Reflux Disease Outcomes Following Roux-en-Y Gastric Bypass Surgery in Patients with Obesity: A Systematic Review and Meta-analysis

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Obesity, defined as BMI > 30 kg/m2, is linked to various co-morbidities, including gastro-oesophageal reflux disease (GORD).
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Roux-en-Y gastric bypass (RYGB) is an effective bariatric surgery that promotes long-term weight loss and resolution of obesity-related co-morbidities.
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The impact of RYGB on GORD outcomes remains uncertain, with insufficient patient-specific data to guide clinical discussions.
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This systematic review aims to evaluate the effects of primary RYGB on GORD symptoms, PPI therapy, and DeMeester scores.
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The study adheres to PRISMA guidelines and includes various study types to assess clinical outcomes of RYGB in managing GORD.

Obesity Surgery

by Narek Sargsyan, Iihan Ali, Christopher Namgoong, Bibek Das, Matyas Fehervari, Michael G. Fadel
April 24, 2025

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