Case report and literature review: the effect of surgical management in intrathoracic pseudomyxoma peritonei

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Intrathoracic pseudomyxoma peritonei is rare and linked to poor prognosis, with no established treatment guidelines.
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Six patients with intrathoracic pseudomyxoma peritonei underwent surgical intervention, with varying degrees of pleural invasion.
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All patients received cytoreductive surgery, with some undergoing hyperthermic intrathoracic chemotherapy to manage symptoms.
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The cohort had a 100% survival rate at 1 year, but only 33.3% at 3 years, indicating a significant drop in long-term survival.
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Postoperative histopathology confirmed low-grade peritoneal pseudomyxoma, emphasizing the need for careful surgical management.

Frontiers In Surgery

by De-Wang Ren, Zhi-Yuan Wang, Li-Bin Miao, Wei-Qiang Lu, Run-Yang Ma, Xue-Jun Dou
May 18, 2026

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