Impact of Omicron Variant on Organ Failure Patterns in Severe COVID-19: A Multicenter Comparison with Wild-Type Strain - Takeaways - MDSpire

Impact of Omicron Variant on Organ Failure Patterns in Severe COVID-19: A Multicenter Comparison with Wild-Type Strain

  • By

  • Ruixuan Yu

  • Ruiqiang Zheng

  • Xufeng Chen

  • Huiying Zhao

  • Jun Jin

  • Changsong Wang

  • Shulin Xiang

  • Man Huang

  • Hongsheng Zhao

  • Yi Wang

  • Nan Shi

  • Hui Chen

  • Yi Yang

  • Jianfeng Xie

  • Haibo Qiu

  • March 5, 2026

  • 0 min

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  • 1

    The Omicron variant of SARS-CoV-2 became the dominant strain globally by January 2022, leading to a significant increase in severe COVID-19 cases in China.

  • 2

    Organ failure is a critical factor influencing prognosis in COVID-19, with variations observed across different SARS-CoV-2 variants.

  • 3

    This study aimed to compare clinical characteristics and organ dysfunction between patients infected with the Omicron variant and the Wild-type strain.

  • 4

    The study included two cohorts: patients with the Omicron variant admitted from December 2022 to January 2023 and Wild-type patients from January to February 2020.

  • 5

    Primary outcomes measured were the incidence of severe COVID-19 and in-hospital mortality, with secondary outcomes including length of hospital stay and organ dysfunction.

Original Source(s)

Impact of Omicron Variant on Organ Failure Patterns in Severe COVID-19: A Multicenter Comparison with Wild-Type Strain

  • by Ruixuan Yu, Ruiqiang Zheng, Xufeng Chen, Huiying Zhao, Jun Jin, Changsong Wang, Shulin Xiang, Man Huang, Hongsheng Zhao, Yi Wang, Nan Shi, Hui Chen, Yi Yang, Jianfeng Xie, Haibo Qiu

  • March 5, 2026

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