PBMC-derived FGF, PDGF, VEGF and GM-CSF secretion in endometriosis: a case–control in vitro study - Takeaways - MDSpire

PBMC-derived FGF, PDGF, VEGF and GM-CSF secretion in endometriosis: a case–control in vitro study

  • By

  • Marcin Sadlocha

  • Aleksandra Krzywon

  • Jakub Marcin Staniczek

  • Jakub Toczek

  • Zenon Czuba

  • Rafal Stojko

  • June 4, 2026

  • 0 min

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  • 1

    Endometriosis is a chronic inflammatory disease characterized by the growth of endometrial-like tissue outside the uterine cavity.

  • 2

    The study evaluated the in vitro secretion of FGF, PDGF, VEGF, and GM-CSF by PBMCs from women with and without endometriosis.

  • 3

    No significant differences in baseline secretion of growth factors were found between women with endometriosis and controls.

  • 4

    PHA stimulation increased FGF, PDGF, and VEGF secretion but did not differ significantly between the two groups after adjustments.

  • 5

    The findings suggest that PBMCs from women with endometriosis do not exhibit systemic hypersecretion of evaluated growth factors.

Original Source(s)

PBMC-derived FGF, PDGF, VEGF and GM-CSF secretion in endometriosis: a case–control in vitro study

  • by Marcin Sadlocha, Aleksandra Krzywon, Jakub Marcin Staniczek, Jakub Toczek, Zenon Czuba, Rafal Stojko

  • June 4, 2026

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