The impact of prevalent primary cancers in melanoma patients on survival - Takeaways - MDSpire
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Influence of Existing Primary Cancers on Survival Outcomes in Melanoma Patients

  • By

  • Alessandra Buja

  • Stefano Guzzinati

  • Chiara Trevisiol

  • Claudio Palmeri

  • Marcello Di Pumpo

  • Paolo Del Fiore

  • Carlo Riccardo Rossi

  • Carmen Stocco

  • Pierfranco Conte

  • Manuel Zorzi

  • Simone Mocellin

  • September 14, 2026

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  • 1

    A study of 2,978 melanoma patients found that 4.5% had prevalent primary cancers diagnosed within five years prior to melanoma.

  • 2

    Common prevalent cancers included prostate (30.2%), breast (10.8%), colon (7.9%), and kidney (7.2%) cancers.

  • 3

    Prevalent tumors were associated with increased all-cause mortality risk, with an adjusted hazard ratio of 1.72.

  • 4

    No significant association was found between prevalent tumors and melanoma-specific mortality.

  • 5

    Healthcare costs were higher for patients with prevalent tumors, averaging €30,698.34 compared to €17,471.23 for those without.

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