The association between time-weighted cumulative life's essential 8 and aortic valve calcification - Takeaways - MDSpire

The association between time-weighted cumulative life's essential 8 and aortic valve calcification

  • By

  • Man Gui

  • Shouling Wu

  • Tonghaoyu Wang

  • Yihao Qi

  • Zhenyu Huo

  • Ying Gao

  • Haiyan Zhang

  • Ying Han

  • Jialing Deng

  • Jing Dong

  • Taiying Wang

  • Shuohua Chen

  • Fengmei Xing

  • May 29, 2026

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  • 1

    The study analyzed 15,321 adults to assess the relationship between the time-weighted cumulative Life's Essential 8 score and aortic valve calcification.

  • 2

    A total of 2,894 cases of aortic valve calcification were identified among participants, with significant associations found between cardiovascular health and AVC.

  • 3

    Moderate cardiovascular health was linked to lower odds of AVC (OR = 0.53), while high cardiovascular health showed even lower odds (OR = 0.25) compared to low health.

  • 4

    A linear inverse association was observed between the TWC-LE8 score and AVC, with a significant trend (P < 0.001) indicating better health correlates with lower AVC.

  • 5

    Among participants aged 55 years and older, high cardiovascular health was associated with 74% lower odds of AVC, while no significant association was found in younger participants.

Original Source(s)

The association between time-weighted cumulative life's essential 8 and aortic valve calcification

  • by Man Gui, Shouling Wu, Tonghaoyu Wang, Yihao Qi, Zhenyu Huo, Ying Gao, Haiyan Zhang, Ying Han, Jialing Deng, Jing Dong, Taiying Wang, Shuohua Chen, Fengmei Xing

  • May 29, 2026

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