Virtual Brain Model Identifies Targeted Stimulation Sites for Altered Neural Activity in Tinnitus - Takeaways - MDSpire

Virtual Brain Model Identifies Targeted Stimulation Sites for Altered Neural Activity in Tinnitus

  • By

  • Jiaqi Zhang

  • Shuting Han

  • Yongcong Shen

  • Xiaojuan Wu

  • Yunshu Zhao

  • Zijia Wu

  • Na Luo

  • Zhengyi Yang

  • Deying Li

  • Ming Song

  • Peng Wu

  • Duo-Duo Tao

  • Jisheng Liu

  • Yonggang Li

  • Tianzi Jiang

  • February 10, 2026

  • 0 min

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  • 1

    Tinnitus is a common neurological disorder linked to abnormal brain activity, affecting perception, emotion, and cognition.

  • 2

    Repetitive transcranial magnetic stimulation (rTMS) shows therapeutic potential for tinnitus by targeting specific brain regions.

  • 3

    The digital twin brain (DTB) model allows for causal simulations of brain activity, enhancing understanding of rTMS effects.

  • 4

    This study is the first to apply DTB in tinnitus, aligning aberrant brain states with resting-state networks.

  • 5

    Validation of DTB-derived response maps demonstrated predictive capacity for rTMS effects in an independent cohort.

Original Source(s)

Virtual Brain Model Identifies Targeted Stimulation Sites for Altered Neural Activity in Tinnitus

  • by Jiaqi Zhang, Shuting Han, Yongcong Shen, Xiaojuan Wu, Yunshu Zhao, Zijia Wu, Na Luo, Zhengyi Yang, Deying Li, Ming Song, Peng Wu, Duo-Duo Tao, Jisheng Liu, Yonggang Li, Tianzi Jiang

  • February 10, 2026

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