A prospective, single-center study included 74 children with SLE and 112 age-matched healthy controls.
2
IG percentage distinguished active SLE from remission with an area under the curve of 0.90, comparable to 0.92 for ESR.
3
At an IG percentage cutoff greater than 0.35%, sensitivity was 81%, specificity was 87%, and diagnostic accuracy was 84%.
4
IG percentage correlated moderately with SLEDAI-2K, clinical SLEDAI-2K, and physician global assessment, while complement C3 showed stronger correlations with disease activity.
5
The authors described WBC inflammatory parameters as complementary measures and noted that small sample size, single-center design, and lack of independent validation limited the study.
