Impact of kimura-takemoto atrophy classification on first-line H. pylori eradication: a retrospective cohort study - Takeaways - MDSpire

Impact of kimura-takemoto atrophy classification on first-line H. pylori eradication: a retrospective cohort study

  • By

  • Dongchu Wang

  • Xiangwu Ding

  • Aixiang Wang

  • June 19, 2026

  • 0 min

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  • 1

    The study analyzed the impact of gastric atrophy grading on H. pylori eradication success using the Kimura-Takemoto classification.

  • 2

    A total of 154 patients were included, with an overall H. pylori eradication rate of 76.6%.

  • 3

    The eradication rate was significantly lower in the open-type atrophy group at 42.3%, compared to 83.6% in the closed-type group.

  • 4

    Multivariate analysis indicated that open-type gastric atrophy was independently associated with an increased risk of eradication failure.

  • 5

    The study suggests caution in using clarithromycin-containing regimens for patients with open-type atrophy and recommends alternative therapies.

Original Source(s)

Impact of kimura-takemoto atrophy classification on first-line H. pylori eradication: a retrospective cohort study

  • by Dongchu Wang, Xiangwu Ding, Aixiang Wang

  • June 19, 2026

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