Patterns of Spread in Ocular Melanoma - Takeaways - MDSpire

Patterns of Spread in Ocular Melanoma

Study examines lymphatic and distant metastasis risk

  • By

  • Jess Allerton

  • February 18, 2026

  • 2 min

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  • 1

    About 25% of patients with conjunctival malignant melanoma developed metastatic disease during long-term follow-up.

  • 2

    Local recurrence occurred in 47% of patients at a mean of 42 months, strongly linked to distant metastasis.

  • 3

    Tumor location and stage significantly influenced metastatic risk, with cT2 tumors showing higher rates than cT1.

  • 4

    Adjuvant therapy reduced systemic spread risk in pT1 tumors, while Ruthenium-106 brachytherapy lowered hematogenous metastasis.

  • 5

    The study's findings may enhance risk stratification and surveillance strategies for patients with conjunctival melanoma.

Original Source(s)

Patterns of Spread in Ocular Melanoma

  • by Jess Allerton

  • February 18, 2026

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