Gastric metastasis from hormone receptor–positive breast cancer ten years after radical mastectomy: a case report and literature review - Takeaways - MDSpire

Gastric metastasis from hormone receptor–positive breast cancer ten years after radical mastectomy: a case report and literature review

  • By

  • Qiang Zhan

  • Gao Wang

  • Hongxia Wan

  • May 15, 2026

  • 0 min

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  • 1

    Gastric metastasis from breast cancer is rare, accounting for 0.3–2% of cases, and can mimic primary gastric malignancy.

  • 2

    A 59-year-old woman developed gastric metastasis of hormone receptor-positive breast cancer 10 years after radical mastectomy.

  • 3

    Diagnosis required endoscopic biopsy and immunohistochemistry due to nonspecific gastrointestinal symptoms.

  • 4

    The patient experienced significant symptom relief and disease stabilization with ribociclib and letrozole treatment.

  • 5

    This case emphasizes the need for awareness of late gastrointestinal metastasis in long-term breast cancer survivors.

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