Association between neutrophil percentage-to-albumin ratio and bone mineral density and prevalent osteoporosis in patients with type 2 diabetes mellitus - Takeaways - MDSpire
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Relationship of Neutrophil Percentage-to-Albumin Ratio with Bone Mineral Density and Osteoporosis Prevalence in Individuals with Type 2 Diabetes Mellitus

  • By

  • Qimin Gao

  • Nuo Jiang

  • Xinxin Liu

  • Xiaoli Wang

  • June 29, 2026

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  • 1

    The study investigated the association between the neutrophil percentage-to-albumin ratio (NPAR) and bone mineral density (BMD) in patients with type 2 diabetes mellitus (T2DM).

  • 2

    NPAR levels were significantly higher in individuals diagnosed with osteoporosis compared to those without osteoporosis (P = 0.004).

  • 3

    NPAR was independently associated with osteoporosis, showing an odds ratio of 3.42 (95% CI: 1.10-10.64, P = 0.034).

  • 4

    There was a negative association between NPAR and BMD at both the femoral neck and total hip, with P-values of 0.009 and 0.020, respectively.

  • 5

    The study concluded that NPAR may provide supplementary information regarding prevalent osteoporosis in patients with T2DM, but should not be used as an independent screening marker.

Original Source(s)

Association between neutrophil percentage-to-albumin ratio and bone mineral density and prevalent osteoporosis in patients with type 2 diabetes mellitus

  • by Qimin Gao, Nuo Jiang, Xinxin Liu, Xiaoli Wang

  • June 29, 2026

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