Association between neutrophil percentage-to-albumin ratio and bone mineral density and prevalent osteoporosis in patients with type 2 diabetes mellitus - Takeaways - MDSpire

Association between neutrophil percentage-to-albumin ratio and bone mineral density and prevalent osteoporosis in patients with type 2 diabetes mellitus

  • By

  • Qimin Gao

  • Nuo Jiang

  • Xinxin Liu

  • Xiaoli Wang

  • June 29, 2026

  • 0 min

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  • 1

    The study investigated the association between the neutrophil percentage-to-albumin ratio (NPAR) and bone mineral density (BMD) in patients with type 2 diabetes mellitus (T2DM).

  • 2

    NPAR levels were significantly higher in individuals diagnosed with osteoporosis compared to those without osteoporosis (P = 0.004).

  • 3

    NPAR was independently associated with osteoporosis, showing an odds ratio of 3.42 (95% CI: 1.10-10.64, P = 0.034).

  • 4

    There was a negative association between NPAR and BMD at both the femoral neck and total hip, with P-values of 0.009 and 0.020, respectively.

  • 5

    The study concluded that NPAR may provide supplementary information regarding prevalent osteoporosis in patients with T2DM, but should not be used as an independent screening marker.

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