Phacoemulsification with goniosynechialysis for nanophthalmos with secondary angle-closure or secondary angle-closure glaucoma: a 20-case series and stepwise management strategy - Takeaways - MDSpire
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Goniosynechialysis Combined with Phacoemulsification for Managing Nanophthalmos Complicated by Secondary Angle-Closure or Angle-Closure Glaucoma: Insights from a Series of 20 Cases and a Stepwise Treatment Approach

  • By

  • Hongyan Zhu

  • Zuohong Wu

  • Yong Wang

  • Xun Zhan

  • Jin Lv

  • Li Ye

  • June 1, 2026

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  • 1

    Nanophthalmos is a rare ocular condition associated with high hyperopia and a shallow anterior chamber, leading to complications like angle-closure glaucoma.

  • 2

    Phacoemulsification combined with goniosynechialysis (Phaco + IOL + GSL) is effective for managing angle-closure glaucoma in patients with nanophthalmos.

  • 3

    This study evaluated 20 patients with nanophthalmos and secondary angle-closure, demonstrating the feasibility and efficacy of the combined surgical approach.

  • 4

    Phaco + IOL + GSL offers a simpler technique and shorter operative time compared to more complex combined surgeries involving vitrectomy or sclerectomy.

  • 5

    The study proposes a stepwise management strategy for postoperative complications, enhancing the overall treatment approach for affected patients.

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