Case Report: Gastric Signet-Ring-Cell Adenocarcinoma in a Young Adult with Tracheoesophageal Fistula/Esophageal Atresia and Complex Gastrointestinal History - Takeaways - MDSpire

Case Report: Gastric Signet-Ring-Cell Adenocarcinoma in a Young Adult with Tracheoesophageal Fistula/Esophageal Atresia and Complex Gastrointestinal History

  • By

  • Katrib, Amira

  • Babun, Asis

  • Wong, Lauren

  • Reynolds, Amberly

  • Nishimura, Makoto

  • April 21, 2026

  • 0 min

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  • 1

    Tracheoesophageal fistula with esophageal atresia can lead to chronic gastrointestinal issues, increasing cancer risk.

  • 2

    A young female with repaired TEF/EA developed gastric signet-ring-cell adenocarcinoma during routine surveillance.

  • 3

    Biopsy errors complicated tumor localization, impacting the management of the identified gastric cancer.

  • 4

    The patient opted for endoscopic surveillance instead of total gastrectomy due to negative imaging and uncertain tumor location.

  • 5

    Over 12 months, the patient showed no malignancy recurrence and significant functional improvement after endoscopic treatment.

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