Vascular and autonomic correlates of screening-positive depressive symptom burden in chronic atrophic gastritis: a multicenter observational study protocol - Takeaways - MDSpire

Vascular and autonomic correlates of screening-positive depressive symptom burden in chronic atrophic gastritis: a multicenter observational study protocol

  • By

  • Meng Wang

  • Shunlei Jiang

  • Zixiang Jin

  • Xinyu Pan

  • Shijie Xu

  • Chao Wang

  • May 5, 2026

  • 0 min

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  • 1

    The study investigates the association between vascular function and depressive symptoms in patients with chronic atrophic gastritis.

  • 2

    It aims to enroll 450–520 adults aged 20–60 years with confirmed chronic atrophic gastritis across four centers in China.

  • 3

    Vascular and autonomic measures will be assessed alongside standardized psychological questionnaires to evaluate depressive symptom burden.

  • 4

    The study seeks to determine if these measures provide additional information beyond conventional clinical and histological variables.

  • 5

    Findings may inform future validation studies and improve multidisciplinary assessment strategies in gastroenterology settings.

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