Association between neutrophil percentage-to-albumin ratio and chronic subdural hematoma: a retrospective case-control study - Takeaways - MDSpire

Relationship Between Neutrophil Percentage-to-Albumin Ratio and Chronic Subdural Hematoma: A Retrospective Case-Control Analysis

  • By

  • Guanda Han

  • Yifan Lv

  • Mingjie Wang

  • Tao Sun

  • Xiaohui Dong

  • Mingliang Deng

  • Hongjie Zhai

  • Hui Zhang

  • Lei Li

  • July 21, 2026

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  • 1

    The study analyzed clinical data from 87 CSDH patients and 130 healthy controls to assess the association between NPAR and CSDH.

  • 2

    NPAR was significantly higher in CSDH patients compared to controls, with a mean of 15.31 ± 2.71 versus 12.47 ± 1.97 (P < 0.001).

  • 3

    Multivariate analysis indicated that NPAR, age, male sex, and lipids were independently associated with CSDH, with an OR of 1.88 for NPAR.

  • 4

    NPAR demonstrated optimal discriminative efficacy for CSDH with an AUC of 0.808, sensitivity of 71.3%, and specificity of 83.8%.

  • 5

    The study concluded that while NPAR is associated with CSDH, its clinical applicability as a diagnostic threshold requires further validation.

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