Venous Thromboembolism and Secondary Outcomes of Bleeding and Mortality in Patients with Gliomas: A Multicenter Cohort Study - Takeaways - MDSpire

Venous Thromboembolism and Secondary Outcomes of Bleeding and Mortality in Patients with Gliomas: A Multicenter Cohort Study

  • By

  • Veiga, Viviane Cordeiro

  • Yamada, Camilla A. F.

  • Clara, Carlos Afonso

  • Santos, Jéssica Carolina Andrade

  • Milano, Breno Gray

  • Matias, Danielli Almeida

  • Melo, Pedro Hortêncio Saboia da Escossia

  • Batistella, Gabriel Novaes de Rezende

  • Cavalcanti, Alexandre Biasi

  • Viola, Fabiana Spillari

  • Levy, Ana Carolina

  • Santos, Silvana Soares

  • Fittipaldi, Carolina

  • Pinto, Mauro Bráulio da Rosa

  • Oliveira, Daniela Galvão Barros

  • Vieira, Thiago Santos

  • Moraes, Flavia Regina

  • Ostolin, Thatiane Lopes Valentim Di Paschoaele

  • Belucci, Talita Rantin

  • Chaddad-Neto, Feres

  • Baeta, Alex Machado

  • Neville, Iuri Santana

  • Peres, Stela Verzinhasse

  • April 30, 2026

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  • 1

    The study analyzed 334 glioma patients across nine Brazilian centers to assess venous thromboembolism (VTE), bleeding, and mortality.

  • 2

    The 12-month cumulative incidence of VTE was 11.8%, while bleeding incidence was 4.7%, and cumulative mortality was 26.2%.

  • 3

    Prior VTE and corticosteroid use significantly increased the risk of VTE, with chronic kidney failure and diabetes predicting bleeding.

  • 4

    Gliomas NOS and GBM were strongly associated with increased mortality risk, alongside factors like longer hospitalization and postoperative bleeding.

  • 5

    Higher educational levels correlated with lower mortality risk, while prolonged hospitalization and postoperative bleeding increased mortality across tumor grades.

Original Source(s)

Venous Thromboembolism and Secondary Outcomes of Bleeding and Mortality in Patients with Gliomas: A Multicenter Cohort Study

  • by Veiga, Viviane Cordeiro, Yamada, Camilla A. F., Clara, Carlos Afonso, Santos, Jéssica Carolina Andrade, Milano, Breno Gray, Matias, Danielli Almeida, Melo, Pedro Hortêncio Saboia da Escossia, Batistella, Gabriel Novaes de Rezende, Cavalcanti, Alexandre Biasi, Viola, Fabiana Spillari, Levy, Ana Carolina, Santos, Silvana Soares, Fittipaldi, Carolina , Pinto, Mauro Bráulio da Rosa, Oliveira, Daniela Galvão Barros, Vieira, Thiago Santos, Moraes, Flavia Regina, Ostolin, Thatiane Lopes Valentim Di Paschoaele, Belucci, Talita Rantin, Chaddad-Neto, Feres , Baeta, Alex Machado, Neville, Iuri Santana, Peres, Stela Verzinhasse

  • April 30, 2026

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