Assessment of anti-nucleocapsid antibody presence as an indicator of SARS-CoV-2 infection among healthcare workers: a longitudinal seroprevalence investigation at a university hospital in Catalonia, Spain - Takeaways - MDSpire

Assessment of anti-nucleocapsid antibody presence as an indicator of SARS-CoV-2 infection among healthcare workers: a longitudinal seroprevalence investigation at a university hospital in Catalonia, Spain

  • By

  • Miquel Micó

  • Jaume Trapé

  • Laura González-García

  • Glòria Trujillo-Isern

  • Carolina González-Fernández

  • Joan López-Madueño

  • Silvia Bérgamo

  • Rafel Pérez-Vidal

  • Antonia Flor

  • Rosa Martínez-Montero

  • Jose Rives

  • Anna Arnau

  • Anna Fàbrega

  • February 6, 2026

  • 0 min

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  • 1

    The study assessed anti-nucleocapsid antibodies to determine SARS-CoV-2 infection rates among healthcare workers in Catalonia, Spain.

  • 2

    Participants included healthcare workers from Althaia Xarxa Assistencial Universitària, with serological tests conducted in two phases.

  • 3

    Detection of anti-N antibodies is crucial for confirming SARS-CoV-2 infection post-vaccination with S protein-based vaccines.

  • 4

    The study utilized electrochemiluminescence immunoassay for anti-N antibody detection, achieving high sensitivity and specificity.

  • 5

    Results indicated the importance of monitoring healthcare workers for SARS-CoV-2 infection to prevent transmission in clinical settings.

Original Source(s)

Assessment of anti-nucleocapsid antibody presence as an indicator of SARS-CoV-2 infection among healthcare workers: a longitudinal seroprevalence investigation at a university hospital in Catalonia, Spain

  • by Miquel Micó, Jaume Trapé, Laura González-García, Glòria Trujillo-Isern, Carolina González-Fernández, Joan López-Madueño, Silvia Bérgamo, Rafel Pérez-Vidal, Antonia Flor, Rosa Martínez-Montero, Jose Rives, Anna Arnau, Anna Fàbrega

  • February 6, 2026

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