Immunotherapy plus induction chemotherapy followed by radiotherapy alone or one cycle of concurrent chemotherapy with cisplatin vs induction chemotherapy followed by two cycles of concurrent chemotherapy with cisplatin in locoregionally advanced nasopharyngeal carcinoma - Takeaways - MDSpire

Immunotherapy plus induction chemotherapy followed by radiotherapy alone or one cycle of concurrent chemotherapy with cisplatin vs induction chemotherapy followed by two cycles of concurrent chemotherapy with cisplatin in locoregionally advanced nasopharyngeal carcinoma

  • By

  • Renba Liang

  • Xinxiao Li

  • Manyi Zhu

  • Fengming Lan

  • Fangmeng Fu

  • Ling Lei

  • Teng Zou

  • Li Ma

  • Peng Chen

  • Lingzhi Luo

  • Jing Jin

  • Jianghu Zhang

  • May 25, 2026

  • 0 min

Share

  • 1

    The study compared immunotherapy combined with induction chemotherapy and radiotherapy to induction chemotherapy with concurrent chemoradiotherapy in nasopharyngeal carcinoma.

  • 2

    A total of 173 patients with locally advanced nasopharyngeal carcinoma were retrospectively analyzed from November 2019 to September 2024.

  • 3

    Complete remission was achieved in 29.4% of the immunochemotherapy group compared to 14.3% in the IC-CCRT group (p=0.02).

  • 4

    The immunochemotherapy group showed a 2-year event-free survival of 93.5% versus 81.1% in the IC-CCRT group (p=0.03).

  • 5

    Grade 3–4 acute adverse events occurred in 41.1% of the immunochemotherapy group and 55.2% of the IC-CCRT group.

Original Source(s)

Immunotherapy plus induction chemotherapy followed by radiotherapy alone or one cycle of concurrent chemotherapy with cisplatin vs induction chemotherapy followed by two cycles of concurrent chemotherapy with cisplatin in locoregionally advanced nasopharyngeal carcinoma

  • by Renba Liang, Xinxiao Li, Manyi Zhu, Fengming Lan, Fangmeng Fu, Ling Lei, Teng Zou, Li Ma, Peng Chen, Lingzhi Luo, Jing Jin, Jianghu Zhang

  • May 25, 2026

Related Content

Follicular dendritic cell sarcoma associated with IgG4-related disease: a case report and literature review

Outcomes of critically ill pediatric patients after haploidentical stem cell transplantation

Longitudinal investigation of psychological adaptation and its determinants in primary caregivers following thyroid cancer surgery