Dosimetric Evaluation of IMRT and VMAT Techniques with Deep Inspiration Breath Hold versus Free Breathing for Whole Breast Irradiation on the Right Side - Takeaways - MDSpire
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Dosimetric Evaluation of IMRT and VMAT Techniques with Deep Inspiration Breath Hold versus Free Breathing for Whole Breast Irradiation on the Right Side

  • By

  • Shing Fung Lee

  • Margaret Cokelek

  • Pui Lam Yip

  • Kaj Bayley

  • Paul Moorfoot

  • Sophie Le-Nguyen

  • Chloe Phung

  • Mark Tacey

  • Yvonne Zissiadis

  • Michael Chao

  • February 25, 2026

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  • 1

    Deep inspiration breath-hold (DIBH) significantly reduces radiation doses to the heart, liver, and lungs in right-sided breast cancer compared to free-breathing (FB).

  • 2

    Intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) enhance dose conformity for whole-breast irradiation in early-stage breast cancer patients.

  • 3

    VMAT demonstrates better target coverage and reduced high-dose exposure to the ipsilateral lung and liver compared to tangential IMRT in right-sided breast cancer.

  • 4

    The study evaluates IMRT and VMAT techniques under both DIBH and FB conditions specifically for right-sided whole-breast irradiation without regional nodal irradiation.

  • 5

    DIBH can improve the therapeutic ratio in right-sided breast radiotherapy by expanding lung volume and lowering the diaphragm during treatment planning.

Original Source(s)

Dosimetric Evaluation of IMRT and VMAT Techniques with Deep Inspiration Breath Hold versus Free Breathing for Whole Breast Irradiation on the Right Side

  • by Shing Fung Lee, Margaret Cokelek, Pui Lam Yip, Kaj Bayley, Paul Moorfoot, Sophie Le-Nguyen, Chloe Phung, Mark Tacey, Yvonne Zissiadis, Michael Chao

  • February 25, 2026

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