Risk factors and prediction model for necrotizing enterocolitis in preterm infants with gestational age ≤ 32 weeks: a retrospective cohort study - Takeaways - MDSpire

Risk factors and prediction model for necrotizing enterocolitis in preterm infants with gestational age ≤ 32 weeks: a retrospective cohort study

  • By

  • Hao Li

  • GuiXiang Zeng

  • YaoXun Wu

  • Lin Cheng

  • LianFang Jing

  • HanLu Zhong

  • Yu Xie

  • Zhe Wei

  • KeMou Wu

  • Jun Fu

  • XiuLi Deng

  • HuaBo Tang

  • RenZhuang Huang

  • YanTing Lin

  • MingJie Lin

  • ShaSha Wei

  • DongMei Jiang

  • Yan Li

  • June 2, 2026

  • 0 min

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  • 1

    A predictive model for necrotizing enterocolitis (NEC) was developed using data from 497 preterm infants in Guangxi, China.

  • 2

    The incidence of NEC among the studied preterm infants was 12.27%, with significant differences in clinical indicators between NEC and non-NEC groups.

  • 3

    Independent risk factors for NEC identified included intrauterine growth restriction, neonatal respiratory distress syndrome, sepsis, and invasive ventilator use.

  • 4

    A higher 5-minute Apgar score was found to be a protective factor against NEC.

  • 5

    The predictive model demonstrated excellent performance with an area under the ROC curve of 0.917 in the training set and 0.906 in the test set.

Original Source(s)

Risk factors and prediction model for necrotizing enterocolitis in preterm infants with gestational age ≤ 32 weeks: a retrospective cohort study

  • by Hao Li, GuiXiang Zeng, YaoXun Wu, Lin Cheng, LianFang Jing, HanLu Zhong, Yu Xie, Zhe Wei, KeMou Wu, Jun Fu, XiuLi Deng, HuaBo Tang, RenZhuang Huang, YanTing Lin, MingJie Lin, ShaSha Wei, DongMei Jiang, Yan Li

  • June 2, 2026

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