Optimizing healthcare resources in pyogenic liver abscess: a dual-threshold HDL-CRP model for predicting hospitalization duration across multi-cohorts - Takeaways - MDSpire

Optimizing healthcare resources in pyogenic liver abscess: a dual-threshold HDL-CRP model for predicting hospitalization duration across multi-cohorts

  • By

  • Mingzhu Tao

  • Muye Xia

  • Suling Chen

  • Guichan Liao

  • Jingchun Mao

  • Shaohang Cai

  • Jie Peng

  • Xuwen Xu

  • April 30, 2026

  • 0 min

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  • 1

    Lower admission high-density lipoprotein cholesterol (HDL-C) levels are independently associated with longer hospital stays for pyogenic liver abscess (PLA).

  • 2

    A dual-threshold model combining HDL-C and C-reactive protein (CRP) effectively identifies patients at high risk for prolonged hospitalization.

  • 3

    The nomogram integrating HDL-C, abscess size, and sepsis demonstrated strong predictive performance for length of stay across multiple cohorts.

  • 4

    Patients with low HDL-C and high CRP levels may require closer monitoring and proactive management to prevent extended hospital stays.

  • 5

    Prospective implementation studies are needed to validate the clinical utility of the HDL-C and CRP dual-threshold model in practice.

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