Impact of the COVID-19 pandemic on the association between sepsis etiology and mortality among ICU patients in France - Takeaways - MDSpire
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Effects of the COVID-19 Pandemic on the Relationship Between Sepsis Causes and Mortality Rates in ICU Patients in France

  • By

  • Marie Al Rahmoun

  • Alexandre Sabaté-Elabbadi

  • Christian Brun-Buisson

  • Laurence Watier

  • September 9, 2026

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  • 1

    Sepsis was estimated to account for approximately 31.5% of global deaths in 2021, underscoring its substantial mortality burden.

  • 2

    Severe COVID-19 can be considered a form of sepsis because it may involve a dysregulated host immune response to SARS-CoV-2 and organ dysfunction or failure.

  • 3

    Previous studies reported higher in-hospital and long-term mortality among patients with sepsis and COVID-19 than among those without COVID-19.

  • 4

    The study evaluated how the COVID-19 pandemic affected associations between sepsis etiology and in-hospital and 90-day mortality among ICU patients in metropolitan France from 2018 through 2022.

  • 5

    Analyses assessed associations between sepsis etiology and in-hospital and 90-day mortality across 3 periods, with patients analyzed separately according to co-infection status.

Original Source(s)

Impact of the COVID-19 pandemic on the association between sepsis etiology and mortality among ICU patients in France

  • by Marie Al Rahmoun, Alexandre Sabaté-Elabbadi, Christian Brun-Buisson, Laurence Watier

  • September 9, 2026

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