Granulomatosis with polyangiitis initially presenting as secretory otitis media: a case report - Takeaways - MDSpire

Granulomatosis with polyangiitis initially presenting as secretory otitis media: a case report

  • By

  • Zhang, Zihan

  • CHEN, YIXI

  • Zeng, Yinping

  • Tang, Zhendong

  • Gu, Jiawei

  • Ma, Wenbo

  • Duan, Tingting

  • Zhou, Xuejun

  • June 8, 2026

  • 0 min

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  • 1

    Granulomatosis with polyangiitis (GPA) is a rare systemic vasculitis that can present with otolaryngological symptoms, often leading to misdiagnosis.

  • 2

    The case study reports a 50-year-old woman whose GPA initially manifested as secretory otitis media, resulting in delayed diagnosis and treatment.

  • 3

    Otolaryngological manifestations of GPA can include hearing loss, facial nerve palsy, and ear pain, complicating the clinical picture.

  • 4

    Early diagnosis of GPA is crucial to prevent serious complications, as otological symptoms may be the sole initial presentation.

  • 5

    The case highlights the importance of multidisciplinary collaboration and vigilance among otolaryngologists for systemic diseases like GPA.

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