Meat Intake, APOE Status Linked to Cognitive Aging

Long-term cohort data suggest genotype-specific associations with cognition, not dementia interaction

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Higher total meat consumption is linked to better cognitive trajectories in older patients with specific APOE genotypes.
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No significant association between meat intake and cognitive change was found in patients with genotypes other than epsilon 3/epsilon 4 or epsilon 4/epsilon 4.
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A higher ratio of processed to total meat intake correlates with increased dementia risk and less favorable cognitive outcomes.
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Subgroup analyses indicated stronger associations between meat intake and cognitive outcomes in females and younger patients.
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The study's findings suggest a potential gene-diet relationship, but limitations include reliance on self-reported dietary data.

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