Link Between Lactate-to-Albumin Ratio and 28-Day Mortality in Older Adults with Sepsis: A Retrospective Analysis of the MIMIC-IV Database - Takeaways - MDSpire

Link Between Lactate-to-Albumin Ratio and 28-Day Mortality in Older Adults with Sepsis: A Retrospective Analysis of the MIMIC-IV Database

  • By

  • Minhui Dai

  • Bowen Yuan

  • Yun Tan

  • February 4, 2026

  • 0 min

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  • 1

    Sepsis significantly affects elderly patients, with ICU mortality rates exceeding 30% in those aged 75 and older.

  • 2

    The lactate-to-albumin ratio (LAR) may enhance prognostic stratification for mortality in elderly sepsis patients.

  • 3

    This study utilized the MIMIC-IV database to analyze the relationship between LAR and 28-day mortality in older adults with sepsis.

  • 4

    A one-unit increase in log-transformed LAR indicates a tenfold increase in the raw LAR, aiding in risk assessment.

  • 5

    Improved identification of high-risk elderly patients with sepsis is crucial for timely intervention and reducing mortality.

Original Source(s)

Link Between Lactate-to-Albumin Ratio and 28-Day Mortality in Older Adults with Sepsis: A Retrospective Analysis of the MIMIC-IV Database

  • by Minhui Dai, Bowen Yuan, Yun Tan

  • February 4, 2026

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