Association of the new TyG indicator–TyHGB with prediabetes and diabetes in middle-aged and elderly postmenopausal women: a longitudinal study - Takeaways - MDSpire

Association of the new TyG indicator–TyHGB with prediabetes and diabetes in middle-aged and elderly postmenopausal women: a longitudinal study

  • By

  • Ziran Xiu

  • Zhengnan Gao

  • Lan Luo

  • Peiyang Yu

  • July 3, 2026

  • 0 min

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  • 1

    The study investigated the association between the TyHGB index and the risk of prediabetes and diabetes in postmenopausal women.

  • 2

    Among 2,138 participants, 598 developed prediabetes and 124 developed diabetes over a three-year follow-up period.

  • 3

    Multivariable logistic regression showed a significant positive association between TyHGB and the risk of both prediabetes and diabetes.

  • 4

    Restricted cubic spline analysis indicated a nonlinear dose-response relationship for prediabetes and diabetes risk with TyHGB.

  • 5

    ROC curve analyses suggested that TyHGB may effectively predict diabetes risk in middle-aged and elderly postmenopausal women.

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