Association of body mass index on 10-year outcomes in patients treated with percutaneous coronary intervention and drug-eluting stents (the DECADE cooperation) - Takeaways - MDSpire

Association of body mass index on 10-year outcomes in patients treated with percutaneous coronary intervention and drug-eluting stents (the DECADE cooperation)

  • By

  • Maria Scalamogna

  • Fiorenzo Simonetti

  • John Joseph Coughlan

  • Luis Ortega-Paz

  • Lorenz Räber

  • Lisette Okkels Jensen

  • Michael Maeng

  • Salvatore Brugaletta

  • Sebastian Kufner

  • Sarah Bär

  • Karl-Ludwig Laugwitz

  • Dik Heg

  • Manel Sabaté

  • Stephan Windecker

  • Kevin Kris Warnakula Olesen

  • Adnan Kastrati

  • Salvatore Cassese

  • November 24, 2025

  • 0 min

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  • 1

    The study analyzed 9486 patients to assess the impact of body mass index on 10-year outcomes after percutaneous coronary intervention with drug-eluting stents.

  • 2

    Underweight patients had a significantly higher risk of all-cause death compared to normal-weight patients, with an adjusted hazard ratio of 1.58.

  • 3

    Overweight patients showed a lower risk of all-cause death and cardiovascular death compared to normal-weight patients, with an adjusted hazard ratio of 0.84.

  • 4

    Both overweight and obese patients had a higher risk of definite stent thrombosis within 30 days post-PCI, while obese patients had a lower risk of repeat revascularization.

  • 5

    The relationship between BMI and long-term outcomes demonstrated a U-shaped association, indicating varying risks for different BMI categories.

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