Electroacupuncture ameliorates embryo implantation dysfunction in mice via miR-30c-5p - Takeaways - MDSpire

Electroacupuncture ameliorates embryo implantation dysfunction in mice via miR-30c-5p

  • By

  • Jing-Yan Song

  • Feng-Yi Dong

  • June 2, 2026

  • 0 min

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  • 1

    Electroacupuncture (EA) improves embryo implantation dysfunction in mice by downregulating miR-30c-5p in the endometrium.

  • 2

    Co-culture with Ishikawa endometrial cells significantly enhances the proliferation and invasion of human trophoblast cells.

  • 3

    Exosomes from Ishikawa and HEC-1-A cells promote trophoblast cell proliferation and invasion, indicating intercellular communication.

  • 4

    In vivo studies show that EA increases implantation sites and reduces endometrial injury in a mouse model of implantation dysfunction.

  • 5

    Inhibition of miR-30c-5p in trophoblast cells leads to increased cell proliferation, invasion, and phosphorylation of FAK and JNK.

Original Source(s)

Electroacupuncture ameliorates embryo implantation dysfunction in mice via miR-30c-5p

  • by Jing-Yan Song, Feng-Yi Dong

  • June 2, 2026

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