The Parity Paradox: How Does Childbearing Impact Breast Cancer Mortality Throughout Life?

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Breast cancer is the most commonly diagnosed malignancy among women and a leading cause of cancer-related mortality worldwide.
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Parity significantly influences breast cancer risk, with each additional pregnancy reducing incidence but potentially increasing mortality.
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Pregnancy-associated breast cancer is characterized by aggressive tumors and worse outcomes due to delayed diagnosis and immune suppression.
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Breastfeeding offers protective benefits against breast cancer, particularly for hormone receptor-negative subtypes.
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The study followed 894,608 Israeli women over 31 years to explore the age-dependent relationship between parity and breast cancer mortality.

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