Romiplostim N01 Enhances Platelet Recovery in Autologous Stem Cell Transplantation with Non-Cryopreserved Peripheral Blood Stem Cells for Plasma Cell Disorders

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Romiplostim N01 significantly accelerates platelet engraftment in autologous stem cell transplantation compared to historical controls.
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Patients receiving Romiplostim N01 achieved complete platelet recovery by day +30 at a rate of 100%, compared to 66.7% in the control group.
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Total hospitalization costs were significantly lower for patients treated with Romiplostim N01, indicating a more economical approach.
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Neutrophil recovery, transfusion requirements, and hospitalization duration were similar between the Romiplostim N01 and control groups.
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The study supports the use of Romiplostim N01 with non-cryopreserved PBSCs as a safe and effective strategy for enhancing thrombopoietic recovery.

Frontiers In Immunology

by Xianfu Sheng, Qijia Zheng, Jingjing Xiang, Nanxi Dong, Yuechao Zhao, Huijin Hu, Lili Qian, Wenbin Liu, Jianping Shen, Baodong Ye, Yu Zhang
April 21, 2026

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