Effects of different negative pressure wound therapy modes on wound healing: a systematic review - Takeaways - MDSpire

Effects of different negative pressure wound therapy modes on wound healing: a systematic review

  • By

  • Cuiyi Wang

  • Xing Liu

  • Yitao Zhou

  • Naqin Liu

  • Yeqin Yang

  • July 2, 2026

  • 0 min

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  • 1

    Negative pressure wound therapy (NPWT) includes three modes: continuous, intermittent, and dynamic, each affecting wound healing differently.

  • 2

    A systematic review included ten clinical studies and fifteen animal studies, focusing on various wound types and healing outcomes.

  • 3

    Intermittent and dynamic NPWT may offer advantages over continuous NPWT in terms of wound healing speed and tissue perfusion.

  • 4

    Current evidence is insufficient to establish a definitive ranking among NPWT modes due to heterogeneity in study designs and outcomes.

  • 5

    Future research should focus on large-scale studies with standardized parameters to clarify the effects and indications of NPWT modes.

Original Source(s)

Effects of different negative pressure wound therapy modes on wound healing: a systematic review

  • by Cuiyi Wang, Xing Liu, Yitao Zhou, Naqin Liu, Yeqin Yang

  • July 2, 2026

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