FOXC1 as a molecular predictor of postoperative peritumoral edema resolution in meningiomas - Takeaways - MDSpire

FOXC1 as a molecular predictor of postoperative peritumoral edema resolution in meningiomas

  • By

  • Alim Emre Basaran

  • Max Braune

  • Alonso Barrantes-Freer

  • Wolf C. Müller

  • Martin Vychopen

  • Erdem Güresir

  • Johannes Wach

  • June 11, 2026

  • 0 min

Share

  • 1

    Meningiomas are the most common primary intracranial tumors, often associated with peritumoral brain edema (PTBE) affecting patient outcomes.

  • 2

    FOXC1 is a transcription factor linked to vascular development and has been associated with preoperative PTBE presence in meningioma patients.

  • 3

    The study aims to evaluate the relationship between FOXC1 expression and postoperative PTBE resolution in meningioma patients.

  • 4

    Postoperative PTBE resolution is defined as the percentage reduction in PTBE volume measured through preoperative and postoperative MRI.

  • 5

    Statistical analyses will identify independent predictors of postoperative PTBE resolution, focusing on FOXC1 as a potential biomarker.

Original Source(s)

FOXC1 as a molecular predictor of postoperative peritumoral edema resolution in meningiomas

  • by Alim Emre Basaran, Max Braune, Alonso Barrantes-Freer, Wolf C. Müller, Martin Vychopen, Erdem Güresir, Johannes Wach

  • June 11, 2026

Related Content

From relapse to survival: real-world clinical impact of a multimodal approach in first-time recurrent glioblastoma

Distribution analysis of gynecological carcinomas with concurrent second primary carcinomas

Case Report: Primary hepatic carcinosarcoma with ectopic β-hCG secretion and a paraneoplastic leukemoid reaction mimicking gynecologic and hematologic disease