Participant Choice of Centralized or Remote Trial Engagement: Secondary Analysis of a Nonrandomized Clinical - Takeaways - MDSpire

Participant Choice of Centralized or Remote Trial Engagement: Secondary Analysis of a Nonrandomized Clinical

  • By

  • Taylor B. Harrison

  • Jessica A. Sinclair

  • Lisa J. Martin

  • William B. Brinkman

  • Melanie F. Myers

  • Michelle L. McGowan

  • May 11, 2026

  • 0 min

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  • 1

    The EAS trial analyzed participant preferences for centralized versus remote engagement in clinical trials using nonrandomized data.

  • 2

    Among 445 participants, 40% chose centralized engagement, 49.9% remote, and 10.1% mixed modalities for study participation.

  • 3

    Young adults preferred centralized engagement, while adolescent-parent dyads favored remote participation, highlighting demographic differences.

  • 4

    Participants living more than 10 miles from CCHMC were more likely to select remote engagement, indicating accessibility challenges.

  • 5

    The trial's hybrid design allowed participant choice, successfully meeting recruitment and visit completion targets for a diverse cohort.

Original Source(s)

Participant Choice of Centralized or Remote Trial Engagement: Secondary Analysis of a Nonrandomized Clinical

  • by Taylor B. Harrison, Jessica A. Sinclair, Lisa J. Martin, William B. Brinkman, Melanie F. Myers, Michelle L. McGowan

  • May 11, 2026

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