Clinical predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis - Takeaways - MDSpire

Clinical predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

  • By

  • Santhosh G. Thavarajasingam

  • Mahmoud El-Khatib

  • Mark Rea

  • Salvatore Russo

  • Johannes Lemcke

  • Lana Al-Nusair

  • Peter Vajkoczy

  • July 8, 2021

  • 0 min

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  • 1

    Idiopathic normal pressure hydrocephalus (iNPH) is characterized by dementia, gait disturbance, and urinary incontinence.

  • 2

    Shunt response (SR) is the gold standard for diagnosing and treating iNPH, with reported improvement rates varying significantly.

  • 3

    Existing guidelines lack explicit diagnostic parameters for tests like the tap test and infusion test, leading to inconsistent evaluations.

  • 4

    This systematic review aims to evaluate the diagnostic effectiveness of clinical features and tests in predicting SR in iNPH.

  • 5

    A total of 35 studies were included in the review, with low to moderate risk of bias and no significant publication bias detected.

Original Source(s)

Clinical predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

  • by Santhosh G. Thavarajasingam, Mahmoud El-Khatib, Mark Rea, Salvatore Russo, Johannes Lemcke, Lana Al-Nusair, Peter Vajkoczy

  • July 8, 2021

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