Epidemiological Analysis of Cardiac Mortality Trends in Patients with Amyloidosis - Takeaways - MDSpire

Epidemiological Analysis of Cardiac Mortality Trends in Patients with Amyloidosis

  • By

  • Abdalhakim Shubietah

  • Diana Owda

  • Mohamed Saad Rakab

  • Yazan Dawoud

  • Ahmed Khraiwesh

  • Mohamed S. Elgendy

  • Mohammed Tareq Mutar

  • Ahmed Emara

  • Ali Saad Al-Shammari

  • Ameer Awashra

  • Mohammed AbuBaha

  • Zaina Nazzal

  • Bandar Alyami

  • Ramesh Daggubati

  • Yasar Sattar

  • December 30, 2025

  • 0 min

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  • 1

    Cardiac amyloidosis significantly contributes to cardiovascular morbidity and mortality, with improved recognition due to advanced imaging techniques.

  • 2

    The study analyzed cardiac-related mortality trends in amyloidosis patients in the U.S. from 1999 to 2020 using CDC WONDER data.

  • 3

    Age-adjusted mortality rates (AAMRs) were computed, and disparities were examined based on sex, race, ethnicity, and geographic region.

  • 4

    Joinpoint regression analysis was utilized to identify significant changes in mortality trends and temporal inflection points.

  • 5

    Machine learning techniques were employed to forecast future AAMRs, aiding public health planning for cardiac amyloidosis.

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