Anthropometry, sex, and age at diagnosis affect pulmonary blood volume quantification from computed tomography pulmonary angiography in pulmonary hypertension assessment

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Anthropometric factors significantly influence pulmonary blood volume measurements in pulmonary hypertension evaluation.
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AI-derived pulmonary blood volumes are affected by sex and age at diagnosis, with distinct impacts on arterial and venous compartments.
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Normalization of pulmonary blood volume to anthropometrics reduces sex-related differences in measurements.
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Larger pulmonary artery volumes correlate with higher pulmonary vascular resistance, while larger pulmonary vein volumes relate to higher cardiac output.
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Incorporating anthropometric data enhances the predictive accuracy of pulmonary vascular resistance and cardiac output models.

Frontiers In Cardiovascular Medicine

by Ghani, Hakim , Thillai, Muhunthan , Walsh, Simon , Bussell, Elliott , Graves, Martin , Pepke-Zaba, Joanna
April 27, 2026

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