Anthropometry, sex, and age at diagnosis affect pulmonary blood volume quantification from computed tomography pulmonary angiography in pulmonary hypertension assessment - Takeaways - MDSpire
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Impact of Anthropometric Factors, Gender, and Age at Diagnosis on Pulmonary Blood Volume Measurement via Computed Tomography Pulmonary Angiography in Evaluating Pulmonary Hypertension

  • By

  • Ghani, Hakim

  • Thillai, Muhunthan

  • Walsh, Simon

  • Bussell, Elliott

  • Graves, Martin

  • Pepke-Zaba, Joanna

  • April 27, 2026

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  • 1

    Anthropometric factors significantly influence pulmonary blood volume measurements in pulmonary hypertension evaluation.

  • 2

    AI-derived pulmonary blood volumes are affected by sex and age at diagnosis, with distinct impacts on arterial and venous compartments.

  • 3

    Normalization of pulmonary blood volume to anthropometrics reduces sex-related differences in measurements.

  • 4

    Larger pulmonary artery volumes correlate with higher pulmonary vascular resistance, while larger pulmonary vein volumes relate to higher cardiac output.

  • 5

    Incorporating anthropometric data enhances the predictive accuracy of pulmonary vascular resistance and cardiac output models.

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