Brief Report on Primary Cutaneous Invasive Aspergillosis in a Patient With Prolonged Neutropenia Following a Traumatic Injury - Takeaways - MDSpire

Brief Report on Primary Cutaneous Invasive Aspergillosis in a Patient With Prolonged Neutropenia Following a Traumatic Injury

  • By

  • Armelle Pérez Cortés Villalobos

  • Ghadeer Alahmadi

  • Coleman Rotstein

  • March 7, 2025

  • 0 min

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  • 1

    Primary cutaneous aspergillosis (PCA) is a rare fungal infection that can occur after skin trauma in immunocompromised patients.

  • 2

    The case involved a patient with acute myeloid leukemia who developed PCA following finger trauma and subsequent neutropenia.

  • 3

    The infection progressed rapidly to a severe necrotizing soft tissue infection, necessitating amputation despite antifungal treatment.

  • 4

    Voriconazole therapy was effective after transitioning from liposomal amphotericin B, highlighting the need for appropriate antifungal management.

  • 5

    This case underscores the importance of thorough medical history and vigilance for invasive fungal infections in neutropenic patients.

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