Predicting lesion reversal in acute cerebral ischaemia via apparent diffusion coefficient threshold on diffusion-weighted MRI - Takeaways - MDSpire

Predicting lesion reversal in acute cerebral ischaemia via apparent diffusion coefficient threshold on diffusion-weighted MRI

  • By

  • Thor Håkon Skattør

  • Atle Bjørnerud

  • Terje Nome

  • Kine Mari Bakke

  • Brian Anthony Enriquez

  • Ingrid Digernes

  • Cecilie Mørck Offersen

  • Mona Kristiansen Beyer

  • Geir Ringstad

  • Anne Hege Aamodt

  • September 29, 2025

  • 0 min

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  • 1

    Rapid assessment of ischaemic lesion extent is vital for acute stroke management and informs decisions about reperfusion therapies.

  • 2

    Diffusion-weighted imaging (DWI) is crucial for early detection of ischaemic changes, but DWI hyperintensities may not indicate irreversible infarction.

  • 3

    The apparent diffusion coefficient (ADC) is essential for assessing tissue viability, with lower values indicating more severe ischaemic injury.

  • 4

    A single ADC threshold may misclassify salvageable tissue as irreversibly damaged, risking exclusion from reperfusion therapies.

  • 5

    The study aims to evaluate a voxel-based ADC threshold's predictive value for lesion reversal in patients undergoing endovascular therapy.

Original Source(s)

Predicting lesion reversal in acute cerebral ischaemia via apparent diffusion coefficient threshold on diffusion-weighted MRI

  • by Thor Håkon Skattør, Atle Bjørnerud, Terje Nome, Kine Mari Bakke, Brian Anthony Enriquez, Ingrid Digernes, Cecilie Mørck Offersen, Mona Kristiansen Beyer, Geir Ringstad, Anne Hege Aamodt

  • September 29, 2025

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