Semiflex-assisted vacuum therapy for perianal fistulas: the Semiflex pilot study - Takeaways - MDSpire

Semiflex-assisted vacuum therapy for perianal fistulas: the Semiflex pilot study

  • By

  • A. J. M. Pronk

  • J. Y. van Oostendorp

  • I. J. M. Han-Geurts

  • S. Madelska

  • C. J. Buskens

  • W. A. Bemelman

  • December 8, 2025

  • 0 min

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  • 1

    Perianal fistulas often result from cryptoglandular sepsis or Crohn's disease, leading to significant pain and reduced quality of life.

  • 2

    The Semiflex pilot study aimed to assess the feasibility of a novel catheter for vacuum therapy in treating perianal fistulas.

  • 3

    The study included two parts: a proof of principle with ten patients and a multicenter feasibility study with an additional center.

  • 4

    Successful catheter exchanges were defined by smooth insertion, proper fixation, maintained vacuum, and acceptable pain levels.

  • 5

    The study's outcomes included clinical closure rates and the overall feasibility of the Semiflex catheter for outpatient use.

Original Source(s)

Semiflex-assisted vacuum therapy for perianal fistulas: the Semiflex pilot study

  • by A. J. M. Pronk, J. Y. van Oostendorp, I. J. M. Han-Geurts, S. Madelska, C. J. Buskens, W. A. Bemelman

  • December 8, 2025

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