Examining the Antibiotic Resistance Patterns of ESKAPE Pathogens from Human Sources in Africa: A Systematic Review and Meta-Analysis - Takeaways - MDSpire
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Examining the Antibiotic Resistance Patterns of ESKAPE Pathogens from Human Sources in Africa: A Systematic Review and Meta-Analysis

  • By

  • Ntelekwane George Khasapane

  • Sebolelo Jane Nkhebenyane

  • Kgaugelo Edward Lekota

  • Oriel Thekisoe

  • Tsepo Ramatla

  • December 22, 2025

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  • 1

    Antibiotic resistance among ESKAPE pathogens in Africa poses a significant public health threat, impacting universal health care and sustainable development goals.

  • 2

    The WHO's priority pathogens list includes critical ESKAPE pathogens like carbapenem-resistant Enterobacterales and methicillin-resistant Staphylococcus aureus.

  • 3

    Recent studies show alarming resistance rates in ESKAPE pathogens, with multidrug resistance reported as high as 84% in Acinetobacter baumannii.

  • 4

    The systematic review aimed to analyze antibiotic resistance patterns of ESKAPE pathogens in Africa from 2014 to 2024, focusing on prevalence and resistance genes.

  • 5

    Misuse and overuse of antibiotics are major drivers of antibiotic resistance, highlighting the need for improved management and administration practices.

Original Source(s)

Examining the Antibiotic Resistance Patterns of ESKAPE Pathogens from Human Sources in Africa: A Systematic Review and Meta-Analysis

  • by Ntelekwane George Khasapane, Sebolelo Jane Nkhebenyane, Kgaugelo Edward Lekota, Oriel Thekisoe, Tsepo Ramatla

  • December 22, 2025

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