Precision treatment of chalazion based on AI-driven risk stratification: a prospective study of triamcinolone acetonide combined with intense pulsed light therapy - Takeaways - MDSpire

Precision treatment of chalazion based on AI-driven risk stratification: a prospective study of triamcinolone acetonide combined with intense pulsed light therapy

  • By

  • Yanlin Zhong

  • Yiming Hu

  • Yuan Lin

  • Huping Wu

  • June 15, 2026

  • 0 min

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  • 1

    The study enrolled 366 patients to evaluate chalazion recurrence rates following different treatment modalities.

  • 2

    Combined therapy of intralesional triamcinolone acetonide and intense pulsed light showed a 95.2% resolution rate at 3 months.

  • 3

    Recurrence rates were significantly lower in the combined therapy group (8.3%) compared to the triamcinolone (15.4%) and IPL-only groups (38.2%).

  • 4

    Demodex infection, age, chronicity, and meibomian gland dysfunction were identified as independent risk factors for recurrence.

  • 5

    The hybrid AI-clinical model improved prediction of recurrence with an AUC of 0.822, outperforming traditional models.

Original Source(s)

Precision treatment of chalazion based on AI-driven risk stratification: a prospective study of triamcinolone acetonide combined with intense pulsed light therapy

  • by Yanlin Zhong, Yiming Hu, Yuan Lin, Huping Wu

  • June 15, 2026

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