Inflammatory Biomarkers and Respiratory Function in Liver Transplant Patients: Findings from a Nationwide Cohort Analysis - Takeaways - MDSpire

Inflammatory Biomarkers and Respiratory Function in Liver Transplant Patients: Findings from a Nationwide Cohort Analysis

  • By

  • Nicoline Arentoft

  • Julie Høgh

  • Hans-Christian Pommergaard

  • Andreas Dehlbæk Knudsen

  • Annette Dam Fialla

  • Paul Suno Krohn

  • Niels Kristian Aagaard

  • Jens-Ulrik Stæhr Jensen

  • Jesper Rømhild Davidsen

  • Michael Perch

  • Allan Rasmussen

  • Susanne Dam Nielsen

  • April 28, 2026

  • 0 min

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  • 1

    Elevated hs-CRP levels are linked to impaired lung function in liver transplant recipients, indicating systemic inflammation's role in this population.

  • 2

    The study included 335 liver transplant recipients, revealing a prevalence of 11.6% for airflow limitation and 24.5% for preserved ratio impaired spirometry.

  • 3

    Median FEV1 and FVC values were 2790 mL and 3680 mL, respectively, with significant associations found between hs-CRP and reduced lung function.

  • 4

    After adjusting for age, sex, ethnicity, BMI, and smoking, hs-CRP >3 mg/L was associated with lower FEV1 and FVC, highlighting its clinical relevance.

  • 5

    This study is the first to explore the relationship between circulating inflammatory markers and lung function in liver transplant recipients.

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