Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis - Takeaways - MDSpire

Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

  • By

  • Santhosh G. Thavarajasingam

  • Mahmoud El-Khatib

  • Kalyan Vemulapalli

  • Hector A. Sinzinkayo Iradukunda

  • Sajeenth Vishnu K.

  • Robin Borchert

  • Salvatore Russo

  • Per K. Eide

  • November 26, 2022

  • 0 min

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  • 1

    Idiopathic normal pressure hydrocephalus (iNPH) is characterized by dementia, urinary incontinence, ataxia, and enlarged ventricles.

  • 2

    The gold standard for diagnosing iNPH is a positive clinical response to shunt surgery, but response rates can vary significantly.

  • 3

    Radiological markers like Evan’s index and callosal angle are recommended for predicting shunt responsiveness in iNPH.

  • 4

    Recent systematic reviews indicate that callosal angle is a better predictor of shunt responsiveness than Evan’s index.

  • 5

    This study aims to be the first meta-analysis evaluating all radiological imaging markers for predicting shunt responsiveness in iNPH.

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