Digital Self-Management of Symptoms and Quality of Life for Patients With Advanced Cancer: A Randomized

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Patients with advanced cancer face significant symptom burden affecting health-related quality of life and increasing emergency department visits.
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Digital symptom-monitoring interventions have shown promise in improving patient-reported outcomes in populations receiving systemic anticancer treatment.
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The Integrated Palliative Outcome Scale (IPOS) was developed to address the multidimensional symptom burden in palliative care settings.
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A multicenter randomized clinical trial evaluated an app-facilitated intervention for symptom monitoring in community-dwelling patients with advanced cancer.
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The primary outcome of the trial was the change in health-related quality of life, measured by the EQ-5D-5L utility score.

Jama Network Open

by Wing-Lok Chan, Inda Sung Soong, Mei-Ying Lim, Winnie Wing-Yan Tin, Steven Wai-Kwan Siu, Jeffrey Ng, Carmen Leung, Alex Leung, Yin-Ling Tai, Ching-Mei Lam, Li-Yu Hou, Raymond Lo, Victor Ho-Fun Lee, Kwok-Keung Yuen, Dora Kwong, Rina Hui
June 1, 2026

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