Relapsing allergic bronchopulmonary aspergillosis as a trigger for Kounis syndrome: a case report - Takeaways - MDSpire
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Kounis Syndrome Induced by Relapsing Allergic Bronchopulmonary Aspergillosis: A Case Study

  • By

  • Haolei Wei

  • Liyan Wu

  • Bin Ni

  • Jingyu Zhang

  • Mengxia Xu

  • Liang Guo

  • Yanping Mao

  • June 9, 2026

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  • 1

    Kounis syndrome is an allergic acute coronary syndrome triggered by hypersensitivity reactions, often underdiagnosed in clinical practice.

  • 2

    A 77-year-old woman with asthma and allergic bronchopulmonary aspergillosis developed Kounis syndrome during an ABPA relapse.

  • 3

    Laboratory tests indicated marked eosinophilia, elevated total IgE, and myocardial injury, with increased cardiac troponin I and BNP.

  • 4

    Coronary angiography revealed nonobstructive coronary arteries, supporting the diagnosis of Kounis syndrome triggered by ABPA.

  • 5

    The patient improved with antifungal therapy, systemic corticosteroids, coronary vasodilators, and supportive care.

Original Source(s)

Relapsing allergic bronchopulmonary aspergillosis as a trigger for Kounis syndrome: a case report

  • by Haolei Wei, Liyan Wu, Bin Ni, Jingyu Zhang, Mengxia Xu, Liang Guo, Yanping Mao

  • June 9, 2026

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