CRRT and ECMO: one love or separate lives? - Takeaways - MDSpire

CRRT and ECMO: one love or separate lives?

  • By

  • Matthieu Schmidt

  • Thomas Rimmelé

  • Kianoush B. Kashani

  • May 18, 2026

  • 0 min

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  • 1

    Acute kidney injury requiring CRRT occurs in up to half of patients supported with ECMO, indicating a significant overlap in critical care needs.

  • 2

    Current guidelines do not endorse a single approach for CRRT during ECMO, reflecting limited evidence and the complexity of extracorporeal circuits.

  • 3

    The E-CRRT trial found no significant difference in CRRT circuit lifespan between integrated and separated ECMO-CRRT configurations.

  • 4

    Both CRRT strategies achieved comparable safety outcomes, with no significant differences in serious adverse events or 28-day mortality.

  • 5

    The trial's crossover design highlights that vascular access limitations often dictate the choice of CRRT strategy in ECMO practice.

Original Source(s)

CRRT and ECMO: one love or separate lives?

  • by Matthieu Schmidt, Thomas Rimmelé, Kianoush B. Kashani

  • May 18, 2026

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