What is ALS, also known as Lou Gehrig's disease? - Takeaways - MDSpire

What is ALS, also known as Lou Gehrig's disease?

  • By

  • Laura Ungar

  • February 20, 2026

  • 0 min

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  • 1

    Eric Dane, an actor, died from amyotrophic lateral sclerosis (ALS) at age 53, less than a year after his diagnosis.

  • 2

    ALS, also known as Lou Gehrig's disease, affects nerve cells in the brain and spinal cord, leading to muscle control loss and paralysis.

  • 3

    The disease is rare, with nearly 33,000 estimated cases in 2022, projected to rise to over 36,000 by 2030, affecting men slightly more than women.

  • 4

    Diagnosis of ALS is challenging due to the absence of specific tests, relying instead on physical exams and symptom observation.

  • 5

    There is no cure for ALS; treatments like riluzole may extend survival, while patients typically live two to five years after symptom onset.

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