Depression as an early symptom and risk factor of dementia - a narrative review - Takeaways - MDSpire

Depression as an early symptom and risk factor of dementia - a narrative review

  • By

  • Agnieszka Permoda-Pachuta

  • Piotr Obszanski

  • Zbigniew Grad

  • Małgorzata Futyma-Jędrzejewska

  • Piotr Ziemecki

  • Monika Dominiak

  • April 10, 2026

  • 0 min

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  • 1

    Depression is a common psychiatric disorder that may serve as an early indicator or risk factor for dementia in older adults.

  • 2

    Late-life depression significantly increases the risk of developing all-cause dementia, particularly vascular dementia.

  • 3

    Differentiating between depression-related cognitive impairment and early dementia is crucial for effective treatment planning.

  • 4

    Neuroimaging techniques like MRI and PET can aid in distinguishing between depression and dementia, despite some limitations.

  • 5

    Understanding the interplay between depression and dementia can enhance early diagnosis and the development of preventive strategies.

Original Source(s)

Depression as an early symptom and risk factor of dementia - a narrative review

  • by Agnieszka Permoda-Pachuta, Piotr Obszanski, Zbigniew Grad, Małgorzata Futyma-Jędrzejewska, Piotr Ziemecki, Monika Dominiak

  • April 10, 2026

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