Impact of Carbohydrate-Adjusted Diets on Insulin Sensitivity Among Overweight and Obese Children and Adolescents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - Takeaways - MDSpire

Impact of Carbohydrate-Adjusted Diets on Insulin Sensitivity Among Overweight and Obese Children and Adolescents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • By

  • Yasaman Khorshidi

  • Nazanin Moslehi

  • Faraneh Zolfaghari

  • Mahdieh Golzarand

  • Golaleh Asghari

  • January 7, 2026

  • 0 min

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  • 1

    Pediatric obesity is linked to serious health risks, including insulin resistance and metabolic syndrome, affecting long-term health outcomes.

  • 2

    The Carbohydrate-Insulin Model suggests that dietary carbohydrate quality and quantity significantly influence insulin sensitivity and weight management.

  • 3

    Previous meta-analyses on carbohydrate-modified diets in children showed inconclusive results regarding their effects on insulin homeostasis.

  • 4

    This systematic review aims to clarify the impact of dietary carbohydrate modifications on fasting insulin and HOMA-IR in overweight and obese youth.

  • 5

    Eligible studies for this review included randomized controlled trials focusing on dietary carbohydrate interventions in children and adolescents.

Original Source(s)

Impact of Carbohydrate-Adjusted Diets on Insulin Sensitivity Among Overweight and Obese Children and Adolescents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • by Yasaman Khorshidi, Nazanin Moslehi, Faraneh Zolfaghari, Mahdieh Golzarand, Golaleh Asghari

  • January 7, 2026

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